Primary or Secondary MR: How Can We Distinguish?
Featuring Dr. James Thomas

Learn More: What criteria do the cardiology team at a Mitral Center of Excellence consider to assess MitraClip^®feasibility? Use our patient screening fact sheet to review the criteria. Download now >

•	Patients who cannot tolerate procedural anticoagulation or post procedural anti-platelet regimen
•	Active endocarditis of the mitral valve
•	Rheumatic mitral valve disease
•	Evidence of intracardiac, inferior vena cava (IVC) or femoral venous thrombus

•	DO NOT use MitraClip outside of the labeled indication. Treatment of non-prohibitive risk DMR patients should be conducted in accordance with standard hospital practices for surgical repair and replacement.
•	MitraClip is intended to reduce mitral regurgitation. The MitraClip procedure is recommended to be performed when an experienced heart team has determined that reduction of MR to ≤2+ is reasonably expected following the MitraClip. If MR reduction to ≤2+ is not achieved, the benefits of reduced symptoms and hospitalizations, improved quality of life, and reverse LV remodeling expected from MitraClip may not occur.
•	The MitraClip Device should be implanted with sterile techniques using fluoroscopy and echocardiography (e.g., transesophageal [TEE] and transthoracic [TTE]) in a facility with on-site cardiac surgery and immediate access to a cardiac operating room.
•	Read all instructions carefully. Failure to follow these instructions, warnings and precautions may lead to device damage, user injury or patient injury. Use universal precautions for biohazards and sharps while handling the MitraClip System to avoid user injury.
•	Use of the MitraClip should be restricted to those physicians trained to perform invasive endovascular and transseptal procedures and those trained in the proper use of the system.
•	The Clip Delivery System is provided sterile and designed for single use only. Cleaning, re-sterilization and/or reuse may result in infections, malfunction of the device or other serious injury or death.
•	Inspect all product prior to use. DO NOT use if the package is opened or damaged.